Signalling to the nucleus under the control of light and small molecules
Samuel Juillot1, Hannes M Beyer1, Josef Madl2
1Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, D-79104 Freiburg, Germany.
Molecular Biosystems
|December 18, 2015
Abstract:
One major regulatory mechanism in cell signalling is the spatio-temporal control of the localization of signalling molecules. We synthetically designed an entire cell signalling pathway, which allows controlling the transport of signalling molecules from the plasma membrane to the nucleus, by using light and small molecules.
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