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Published on: September 26, 2018
Bushehr Elderly Health (BEH) Programme, phase I (cardiovascular system)
Afshin Ostovar1, Iraj Nabipour2, Bagher Larijani3
1The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.
Insights
This study investigated cardiovascular disease risk factors in elderly Iranians, finding a higher prevalence in women. Ongoing follow-up will track major adverse cardiac events in this cohort.
Area of Science:
- Gerontology
- Cardiology
- Epidemiology
Background:
- Cardiovascular diseases (CVDs) are a leading cause of mortality globally, particularly in aging populations.
- Understanding the prevalence and patterns of CVD risk factors in specific demographics is crucial for targeted interventions.
- The Bushehr Elderly Health Programme (BEHP) was initiated to address the health needs of the elderly in Iran.
Purpose of the Study:
- To determine the prevalence of cardiovascular risk factors in individuals aged 60 and above in Bushehr, Iran.
- To examine the association between these risk factors and major adverse cardiovascular events (MACE).
- To establish a baseline for longitudinal monitoring of cardiovascular health in the elderly Iranian population.
Main Methods:
- A prospective cohort study involving 3000 participants (men and women ≥ 60 years) in Bushehr, Iran.
- Data collection included modified WHO MONICA questionnaire for risk factors, anthropometric measurements, blood pressure, electrocardiography, and echocardiography.
- Blood samples were collected and stored for future analyses.
Main Results:
- Preliminary analysis indicates a higher prevalence of cardiovascular risk factors among older women compared to older men.
- Baseline data on demographic, socioeconomic, smoking, and medical history were collected.
- Vital signs, anthropometric measures, ECG, and echocardiography were performed on all participants.
Conclusions:
- The initial findings highlight potential sex-based differences in cardiovascular risk factor prevalence among the elderly in Bushehr.
- The BEHP provides a valuable dataset for understanding and mitigating cardiovascular disease in this population.
- Further follow-up is planned to assess the incidence of MACE and investigate other health aspects like bone health and cognition.
Purpose:
The main objective of the Bushehr Elderly Health Programme, in its first phase, is to investigate the prevalence of cardiovascular risk factors and their association with major adverse cardiovascular events.
Participants:
Between March 2013 and October 2014, a total of 3000 men and women aged ≥ 60 years, residing in Bushehr, Iran, participated in this prospective cohort study (participation rate=90.2%).
Findings To Date:
Baseline data on risk factors, including demographic and socioeconomic status, smoking and medical history, were collected through a modified WHO MONICA questionnaire. Vital signs and anthropometric measures, including systolic and diastolic blood pressure, weight, height, and waist and hip circumference, were also measured. 12-lead electrocardiography and echocardiography were conducted on all participants, and total of 10 cc venous blood was taken, and sera was separated and stored at -80 °C for possible future use. Preliminary data analyses showed a noticeably higher prevalence of risk factors among older women compared to that in men.
Future Plans:
Risk factor assessments will be repeated every 5 years, and the participants will be followed during the study to measure the occurrence of major adverse cardiac events. Moreover, the second phase, which includes investigation of bone health and cognition in the elderly, was started in September 2015. Data are available at the Persian Gulf Biomedical Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran, for any collaboration.
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