Related Experiment Video
Updated: Mar 28, 2026

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
Published on: December 7, 2013
Asymptomatic aortic mural thrombus in a minimally atherosclerotic vessel
Alessandro Maloberti1, Fabrizio Oliva2, Benedetta De Chiara3
1Department of Health Science, Milano-Bicocca University, Milan, Italy.
Abstract:
Aortic mural thrombi in a normal (non-aneurysmal or minimally atherosclerotic) vessel are an uncommon condition. They are usually located in the descending aorta and, less frequently, in the aortic arch or in the abdominal aorta. The typical clinical presentation is the appearance of symptoms/signs of peripheral arterial embolization, such as lower limb or visceral ischaemia, but these can also be accidentally found in asymptomatic patients. We report the case of a 40-year old man with untreated hypertension and dyslipidaemia admitted to hospital for atypical chest pain associated with an elevation in high-sensitivity troponin T with normal creatine kinase isoenzime MB creatine kinase isoenzyme. Elektrocardiogram (EKG) and transthoracic echocardiography were non-diagnostic; in order to exclude an aortic dissection, a gated chest computed tomography was performed and showed an aortic thrombus on a minimally atherosclerotic wall. Then, a transoesophageal echocardiography confirmed an aortic floating thrombus (7 × 4 mm). Cardiac surgeons advised against surgery and therapy with antiplatelet, low molecular weight heparin, β-blocker, antihypertensive and lipid-lowering drugs was initiated. A complete resolution of the thrombus was observed at the 12-day tomographic control.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Atherosclerosis I: Introduction
Aneurysm III: Interprofessional Care
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Aneurysm I: Introduction

