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Updated: Mar 28, 2026

Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles
Published on: March 28, 2021
Comprehensive understanding of nano-sized particle separation processes using nanoparticle tracking analysis
Desmond F Lawler1, Sungmin Youn1, Tongren Zhu1
1Department of Civil, Architectural and Environmental Engineering, University of Texas, One University Station C1786, Austin, TX, USA
Abstract:
The understanding of nano-sized particle separation processes has been limited by difficulties of nanoparticle characterization. In this study, nanoparticle tracking analysis (NTA) was deployed to evaluate the absolute particle size distributions in laboratory scale flocculation and filtration experiments with silver nanoparticles. The results from NTA were consistent with standard theories of particle destabilization and transport. Direct observations of changes in absolute particle size distributions from NTA enhance both qualitative and quantitative understanding of particle separation processes of nano-sized particles.
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