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Updated: Mar 28, 2026
Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research
Published on: June 8, 2022
Tri-band spectroscopic optical coherence tomography based on optical parametric amplification for lipid and vessel
Luoqin Yu1, Jiqiang Kang1, Chandra Jinata1
1The University of Hong Kong, Photonic Systems Research Laboratory, Department of Electrical and Electronic Engineering, Pokfulam Road, Hong Kong, China.
Abstract:
A tri-band spectroscopic optical coherence tomography (SOCT) system has been implemented for visualization of lipid and blood vessel distribution. The tri-band swept source, which covers output spectrum in 1.3, 1.5, and 1.6 μm wavelength windows, is based on a dual-band Fourier domain mode-locked laser and a fiber optical parametric amplifier. This tri-band SOCT can further differentiate materials, e.g., lipid and artery, qualitatively by contrasting attenuation coefficients difference within any two of these bands. Furthermore, ex vivo imaging of both porcine artery with artificial lipid plaque phantom and mice with coronary artery disease were demonstrated to showcase the capability of our SOCT.
