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Lupus Erythematosus Panniculitis in Pregnancy
Swati Gondane1, Rajkumar Kothiwala1, Sapna Dangi1
1Department of Dermatology, Venereology and Leprosy, JLN Medical College and Associated Group of Hospitals, Ajmer, Rajasthan, India.
Indian Journal of Dermatology
|December 18, 2015
Summary
This case report details lupus erythematosus panniculitis during pregnancy, presenting without typical discoid or systemic lupus signs. The condition successfully responded to steroid treatment, highlighting a unique presentation.
Area of Science:
- Dermatology
- Rheumatology
- Obstetrics
Background:
- Lupus erythematosus (LE) panniculitis is a rare manifestation of LE.
- Pregnancy can alter the course of autoimmune diseases, including lupus.
- Panniculitis as the sole manifestation of LE during pregnancy is uncommon.
Purpose of the Study:
- To report a unique case of lupus erythematosus panniculitis occurring during pregnancy.
- To highlight the clinical and histopathological diagnostic criteria in the absence of systemic or discoid LE.
- To discuss the management and outcome of this rare condition.
Main Methods:
- Case presentation of a pregnant patient with panniculitis.
- Clinical examination and histopathological analysis of skin lesions.
- Laboratory investigations including antinuclear antibody (ANA) and specific autoantibodies (anti-dsDNA, anti-Ro/SSA, anti-La/SSB).
Main Results:
- The patient presented with panniculitis without discoid or systemic lupus erythematosus.
- All immunological markers (ANA, anti-dsDNA, anti-Ro/SSA, anti-La/SSB) were within normal limits.
- Skin biopsy confirmed lupus panniculitis.
- Favorable response to systemic steroid therapy was observed.
Conclusions:
- Lupus erythematosus panniculitis can occur during pregnancy as an isolated finding.
- Diagnosis relies on clinical and histopathological evaluation, even with normal serological markers.
- Systemic steroids are an effective treatment for lupus panniculitis in pregnancy.
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