Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of Medium Optimization01:28

Methods of Medium Optimization

45
Optimizing growth media enhances microbial proliferation and maximizes product yield. Statistical experimental design methodologies provide structured and reproducible approaches, offering progressively higher levels of robustness and efficiency.The One-Factor-at-a-Time (OFAT) MethodThe One-Factor-at-a-Time (OFAT) method involves adjusting a single variable while keeping all others constant. However, it cannot detect interactions between variables, often leading to suboptimal outcomes when...
45
Response Surface Methodology01:16

Response Surface Methodology

822
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
822

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025
Same author

Comparison of the potency-ratio of ciprofol and propofol on sedative effects in painless hysteroscopy: a randomized double-blind dose-response study.

BMC anesthesiology·2025
Same author

Multifunctional Co-FeS<sub>2</sub> nanozyme-hydrogel composite promotes diabetic wound healing by synergistic antioxidant, antibacterial, and anti-inflammation therapy.

Journal of colloid and interface science·2025
Same author

Different responses of luminal and glandular epithelium during mouse embryo implantation.

Frontiers in veterinary science·2025
Same author

Long-Term Outcomes of Triple Cannulated Compression Screws Combined With Bone Graft Sleeve Parallel Implantation of DBM Crunch Internal Fixation for the Treatment of Femoral Neck Fractures in Middle-Aged and Young Adults.

Orthopaedic surgery·2025
Same author

Two-Dimensional Hybrid SnO<sub>2</sub>@WO<sub>3</sub> Nanosheets Synthesized by Polyoxometallate Cluster-Nucleus Coassembly for Highly Efficient H<sub>2</sub> Detection.

ACS sensors·2025

Related Experiment Video

Updated: Mar 28, 2026

Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
06:00

Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development

Published on: March 17, 2023

956

[Optimization of extraction technology from Paeoniae Radix Alba using response surface methodology].

Lin Jin, Wan-shun Zhao, Qiao-sheng Guo

    Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
    |December 19, 2015
    PubMed
    Summary

    This study optimized ultrasonic-assisted extraction for Paeoniae Radix Alba, yielding improved component recovery. The enhanced method offers advantages over traditional Chinese Pharmacopoeia extraction techniques.

    More Related Videos

    Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
    09:16

    Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method

    Published on: May 12, 2023

    1.7K
    Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
    09:12

    Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method

    Published on: May 19, 2023

    1.2K

    Related Experiment Videos

    Last Updated: Mar 28, 2026

    Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
    06:00

    Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development

    Published on: March 17, 2023

    956
    Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method
    09:16

    Author Spotlight: Optimization of Processing Technology for Tiebangchui with Zanba Based on CRITIC Combined with Box-Behnken Response Surface Method

    Published on: May 12, 2023

    1.7K
    Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
    09:12

    Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method

    Published on: May 19, 2023

    1.2K

    Area of Science:

    • Phytochemistry
    • Analytical Chemistry
    • Process Optimization

    Context:

    • Paeoniae Radix Alba (White Peony Root) is a traditional herbal medicine.
    • Ensuring stability and operational convenience in extraction processes is crucial.
    • Ultrasound-assisted extraction (UAE) is explored for its efficiency.

    Purpose:

    • To optimize the UAE conditions for Paeoniae Radix Alba extraction.
    • To identify key factors influencing extraction efficiency, including time, ethanol concentration, and liquid-to-solid ratio.
    • To validate the optimized extraction parameters against established methods.

    Summary:

    • Single factor methodology and response surface methodology were employed to optimize UAE parameters.
    • Ethanol concentration was found to be the most significant factor, followed by liquid-to-solid ratio and extraction time.
    • Optimal conditions determined: 20.06 min extraction time, 72.04% ethanol concentration, and 53.38 mL/g liquid-to-solid ratio.

    Impact:

    • The optimized UAE method achieved a predicted total common peaks area of 2.1608 x 10^8, with an experimental validation of 2.1422 x 10^8 (0.86% deviation).
    • This optimized technology is suitable, feasible, and demonstrates superior extraction efficiency compared to the Chinese Pharmacopoeia method.
    • The findings facilitate comprehensive assessment and utilization of Paeoniae Radix Alba components.