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Published on: March 5, 2022
ViralEpi v1.0: a high-throughput spectrum of viral epigenomic methylation profiles from diverse diseases
Mohd Shoaib Khan1, Amit Kumar Gupta1, Manoj Kumar1
1Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific & Industrial Research (CSIR), Sector 39-A, Chandigarh-160036, India.
Aims:
To develop a computational resource for viral epigenomic methylation profiles from diverse diseases.
Materials & Methods:
Methylation patterns of Epstein-Barr virus and hepatitis B virus genomic regions are provided as web platform developed using open source Linux-Apache-MySQL-PHP (LAMP) bundle: programming and scripting languages, that is, HTML, JavaScript and PERL.
Results:
A comprehensive and integrated web resource ViralEpi v1.0 is developed providing well-organized compendium of methylation events and statistical analysis associated with several diseases. Additionally, it also facilitates 'Viral EpiGenome Browser' for user-affable browsing experience using JavaScript-based JBrowse.
Conclusion:
This web resource would be helpful for research community engaged in studying epigenetic biomarkers for appropriate prognosis and diagnosis of diseases and its various stages.
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