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Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
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[Implant Design by Means of Multiphoton Polymerization].

U Hinze1, A El-Tamer1, S Reiß2

  • 1Nanotechnologie, Laser Zentrum Hannover e. V.

Klinische Monatsblatter Fur Augenheilkunde
|December 19, 2015
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Summary

High-resolution 3D printing using multiphoton polymerization (MPP) successfully manufactured complex multifocal intraocular lenses. This technology shows promise for customized, on-demand production of patient-specific eye implants.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Optics

Background:

  • Additive manufacturing and 3D printing offer novel approaches for implant design and production.
  • High-resolution technologies are crucial for developing microstructured ocular implants.
  • This study explores 3D printing for designing and manufacturing multifocal diffractive aspheric intraocular lenses.

Purpose of the Study:

  • To demonstrate the application of high-resolution 3D printing in creating advanced intraocular lenses.
  • To develop a multifocal diffractive aspheric intraocular lens using specific 3D printing techniques.

Main Methods:

  • Multiphoton polymerization (MPP) was employed for sub-micrometer resolution diffractive relief manufacturing.
  • The diffractive relief was integrated onto a refractive lens mold to create a trifocal lens.
  • Light propagation through the lens was visualized in fluorescein-infused water.

Main Results:

  • Successful fabrication of multifocal lenses was achieved.
  • Optical design with three focal points was validated by light propagation imaging.
  • Images effectively illustrated the effects of refractive and diffractive elements, highlighting potential artifacts and aberrations.

Conclusions:

  • Multiphoton polymerization (MPP) is a versatile tool for manufacturing intricate multifocal lenses.
  • Advancements in MPP-based 3D printing position it as a promising method for patient-specific, on-demand intraocular lens production.