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Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
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Guided Bone Regeneration Using Demineralized Dentin Matrix: Long-Term Follow-Up
Young-Kyun Kim1, Jong-Ho Lee2, In-Woong Um3
1Professor, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam; Professor, Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
Summary
Demineralized dentin matrix (AutoBT) shows successful long-term bone maintenance for guided bone regeneration. This study confirms AutoBT
Area of Science:
- Oral surgery
- Regenerative medicine
- Dental implantology
Background:
- Autogenous tooth bone graft material (AutoBT) is used for guided bone regeneration.
- Long-term clinical outcomes of AutoBT require further investigation.
Purpose of the Study:
- To review the long-term clinical outcomes of AutoBT in 5 cases.
- To assess bone maintenance and resorption after AutoBT grafting.
Main Methods:
- Cone-beam computerized tomography (CBCT) for bone height and width measurements.
- Histological evaluation of corticocancellous bone formation and marginal bone resorption.
- Average follow-up period of 5 years and 5.8 months.
Main Results:
- Bone area changes ranged from -8.1% to -36.2%.
- Buccal height and alveolar ridge width decreased between -0.4 to -3.3 mm and -0.4 to -4.2 mm, respectively.
- Successful maintenance of corticocancellous bone with minimal resorption (1 mm) in one case.
Conclusions:
- AutoBT demonstrates successful long-term maintenance of regenerated bone for implant placement.
- Results are consistent with short-term AutoBT studies.
- Further research with larger sample sizes is warranted.
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