Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Efficient selection of tests for bacteriological typing schemes.

M A Gaston¹, P R Hunter

¹Central Public Health Laboratory, Colindale, London.

Journal of Clinical Pathology

|July 1, 1989

Summary

A new computerized method simplifies selecting bacteriological typing tests using a numerical index of discrimination (D). This approach efficiently identifies the most effective combination of tests for bacterial identification and characterization.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Regional differences in presence of Shiga toxin-producing Escherichia coli virulence-associated genes in the environment in the North West and East Anglian regions of England.

Letters in applied microbiology·2020

Same author

An agent-based model about the effects of fake news on a norovirus outbreak.

Revue d'epidemiologie et de sante publique·2020

Same author

Serological responses to Cryptosporidium antigens in inhabitants of Hungary using conventionally filtered surface water and riverbank filtered drinking water.

Epidemiology and infection·2015

Same author

Longitudinal surveillance of bacteraemia in haematology and oncology patients at a UK cancer centre and the impact of ciprofloxacin use on antimicrobial resistance.

The Journal of antimicrobial chemotherapy·2013

Same author

School-based sex education is associated with reduced risky sexual behaviour and sexually transmitted infections in young adults.

Public health·2012

Same author

Foreign travel, casual sex, and sexually transmitted infections: systematic review and meta-analysis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2010

Area of Science:

Microbiology
Computational Biology
Bioinformatics

Background:

Bacteriological typing methods like bacteriophage, bacteriocin, and biotyping are crucial for bacterial identification and epidemiology.
Selecting an optimal set of tests for these methods can be complex and time-consuming.

Purpose of the Study:

To develop and assess a computerized method for simplifying the selection of efficient bacteriological typing test sets.
To utilize a numerical index of discrimination (D) to guide the selection process.

Main Methods:

A computer program was developed to iteratively select tests that maximize the numerical index of discrimination (D).
The program starts with the most discriminatory test and sequentially adds tests that further enhance discrimination.
Options for pre-selecting or excluding specific tests were incorporated.

Related Experiment Videos

Main Results:

The computerized method effectively selects discriminatory typing sets by maximizing the index D.
The process ensures that each added test contributes to the overall discriminatory power of the typing set.

Conclusions:

The numerical index D provides a simple and effective means for selecting bacteriological typing tests.
The method's utility is enhanced when combined with data on test reaction incidence, reproducibility, and similarity.