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[OPTIMIZATION OF GLUCOSE METABOLISM IN PATIENTS UNDERGOING THERAPEUTIC HYPOTHERMIA AFTER SUDDEN CARDIAC ARREST]

Cristina Prieto Robles, Ana Argibay Lago, Alexandre Hernanz Del Río

    Revista De Enfermeria (Barcelona, Spain)
    |December 22, 2015
    PubMed

    Insights

    Therapeutic hypothermia (TH) for sudden cardiac arrest (SCA) survivors showed improved glycemic control with a specific insulin protocol. This approach reduced blood glucose alterations during TH stages, with low hypoglycemia rates.

    Area of Science:

    • Cardiology
    • Intensive Care Medicine
    • Endocrinology

    Context:

    • Therapeutic hypothermia (TH) is a critical intervention for sudden cardiac arrest (SCA) survivors.
    • Glycemic control in patients undergoing TH is not well-established.
    • This study investigates glycemic management during TH.

    Purpose:

    • To evaluate the effectiveness of a specific insulin protocol for glycemic control in SCA survivors treated with TH.
    • To analyze glycemic levels across different stages of TH (induction, maintenance, rewarming).

    Summary:

    • A retrospective analysis of 49 SCA survivors treated with TH and a specific insulin protocol was conducted.
    • High rates of glycemic alteration were observed during the induction stage, decreasing significantly by the rewarming stage (95.9% to 69.4%).
    • The protocol resulted in low rates of severe hypoglycemia (12%), in-hospital mortality (20%), and anoxic encephalopathy (27%).

    Impact:

    • The findings suggest that a dedicated insulin protocol can improve blood glucose management in patients undergoing TH.
    • Further research is warranted to confirm the clinical impact of such protocols on patient outcomes.
    • This study provides valuable insights for optimizing care protocols in post-SCA management.
    Abstract

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