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Updated: Mar 28, 2026

Evaluating Targeting Accuracy in the Focal Plane for an Ultrasound-guided High-intensity Focused Ultrasound Phased-array System
Published on: March 6, 2019
[Detectability of High Intensity Areas in FLAIR and Multi Shot EPI-FLAIR: Phantom Study]
Yu Takakura1, Hitoshi Usuniwa, Hiroyuki Muranaka
1Department of Radiology, Toride Kitasoma Health Medical Center Medical Association Hospital.
Abstract:
In magnetic resonance imaging (MRI) of brain, fast spin echo-fluid attenuated inversion recovery (FSE-FLAIR) is widely used to detect high intensity areas (HIAs). The way of getting FLAIR contrast at high speed includes echo planar imaging-FLAIR (EPI-FLAIR), and in EPI-FLAIR there are single shot EPI-FLAIR (SS-EPI-FLAIR) and multi shot EPI-FLAIR (MS-EPI-FLAIR). There were negative opinions for the reports of SS-EPI-FLAIR, and it is reported that SS-EPI-FLAIR is able to acquire image quality that is equal to FSE-FLAIR in a shorter time, recently. But there are few reports that utilized contrast of MS-EPI-FLAIR. Our object was to compare HIA detectability in FSE-FLAIR and MS-EPI-FLAIR in equal imaging time, and to evaluate a basic characteristic. We dissolved indigestive dextrin in the aqua destillata and created a 0-46 wt% phantom. The concentration that correspond to T1, T2 value of brain white matter was 42 wt%. We calculated contrast by using signal intensities of each phantom, and compared contrast by signal intensities of each phantom, and compared the contrast of MS-EPI-FLAIR and FSE-FLAIR. In the range of 18-46 wt%, the contrast of MS-EPI-FLAIR was positive value, and that of FSE-FLAIR was 26-42 wt%. By the statistical test, contrast of MS-EPI-FLAIR in 18-26% was significantly different for FSE-FLAIR. In conclusion, it was suggestive that MS-EPI-FLAIR is able to detect HIA equally or sharply.

