Uterine involvement in guineapig salmonellosis

Of 334 mature breeding guineapigs, 53 (15.9%) died in a disease outbreak involving Salmonella typhimurium serotypes 1, 4, 5 and 12 : i : 1,2. The uterus was consistently involved. Nine other Salmonella-free mature female guineapigs when inoculated with a pure isolate from the outbreak, using the subcutaneous, intramuscular or per os route, succumbed to salmonellosis, reproducing signs and lesions observed during the outbreak. Abortion was not recorded during the outbreak despite many pregnant sows being affected. The isolate was sensitive to gentamicin, tetracycline, ampicillin and cefuroxime but resistant to co-trimoxazole, erythromycin and penicillin.