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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
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Induction Therapy for Mesothelioma.

Isabelle Opitz1, Walter Weder2

  • 1Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland..

Seminars in Thoracic and Cardiovascular Surgery
|December 22, 2015
PubMed
Summary
This summary is machine-generated.

Induction therapy before surgery can downstage mesothelioma, making tumors resectable. This review examines the principles and outcomes of various induction treatment modalities for mesothelioma.

Keywords:
Extrapleural Pneumonectomy.MCRMPMPleurectomy and Decorticationinduction therapy

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Area of Science:

  • Oncology
  • Thoracic Surgery

Background:

  • Mesothelioma treatment often involves multimodality approaches.
  • Induction therapy followed by surgery is a key strategy.

Purpose of the Study:

  • To review the principles of induction therapy for mesothelioma.
  • To evaluate the outcomes of different induction treatment modalities.

Main Methods:

  • Review of existing literature on mesothelioma induction therapy.
  • Analysis of treatment principles and patient outcomes.

Main Results:

  • Induction therapy can downstage mesothelioma, improving resectability.
  • Potential increase in treatment-related morbidity and mortality exists.

Conclusions:

  • Induction therapy is a critical component of multimodality mesothelioma treatment.
  • Careful consideration of risks and benefits is necessary.