Why do patients participate in long-term cardiovascular trials?--a questionnaire-based study

Area of Science:

• Cardiology
• Clinical Research
• Patient Engagement

Background:

• Patient participation is crucial for developing new cardiovascular disease treatments.
• Long-term clinical trials require high patient retention to yield valid results.
• Understanding patient motivations can improve trial recruitment and reduce dropout rates.

Purpose of the Study:

• To identify key motivators for patient participation and retention in long-term cardiovascular clinical trials.
• To inform strategies for enhancing patient enrollment and adherence in clinical research.

Main Methods:

• A questionnaire with 11 statements was administered to 135 participants in cardiovascular clinical trials.
• Participants' reasons for joining and remaining in trials were assessed.
• Demographic data including age and gender were collected.

Main Results:

• The primary motivator for participation was consistent access to their doctor and nurse (66%).
• A strong secondary motivator was the desire to advance scientific knowledge (55%).
• Free visits were the least significant factor influencing participation.

Conclusions:

• Continuous care and a familiar healthcare team are significant drivers for patient involvement in cardiovascular trials.
• Altruistic motivations, such as contributing to scientific progress, are equally important for patient retention.
• Addressing these motivators can enhance patient recruitment and long-term commitment in clinical research.