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Comparative clinical study on the efficacy of biocor plus compared with simvastatin for the management of

Zeeshan Sheikh Sheikh1, Khan Usmanghani1, Halima Nazar2

  • 1Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan / Department of Research and Development, Herbion Pakistan (Pvt) Limited, Korangi Industrial Area, Karachi, Pakistan.

Pakistan Journal of Pharmaceutical Sciences
|December 22, 2015
PubMed

Insights

Biocor Plus effectively normalized lipid profiles in patients with hypercholesterolemia, showing significant therapeutic value compared to Simvastatin. This herbal drug demonstrated good patient acceptability with no significant side effects.

Area of Science:

  • Cardiovascular Medicine
  • Pharmacology
  • Herbal Medicine

Background:

  • Hypercholesterolemia is a significant risk factor for cardiovascular and coronary artery diseases.
  • Effective management of high cholesterol is crucial for public health.
  • Existing treatments like Simvastatin have established efficacy but may have side effects.

Purpose of the Study:

  • To evaluate the efficacy of Biocor Plus in normalizing lipid profiles in patients with hypercholesterolemia.
  • To compare the effectiveness of Biocor Plus with Simvastatin, a standard treatment.
  • To assess the safety and patient acceptability of Biocor Plus.

Main Methods:

  • A prospective randomized case-control study was conducted on 70 diagnosed hypercholesterolemia patients (30-70 years old).
  • Participants received either Biocor Plus or Simvastatin.
  • Lipid profiles were monitored, and patient outcomes including side effects and well-being were assessed.

Main Results:

  • Biocor Plus demonstrated a statistically significant difference in effectiveness compared to Simvastatin for treating primary hypercholesterolemia.
  • The herbal drug, Biocor Plus, showed clear therapeutic value in managing high cholesterol levels.
  • No significant adverse side effects were reported with Biocor Plus, indicating good patient acceptability.

Conclusions:

  • Biocor Plus is an effective alternative treatment for primary hypercholesterolemia.
  • The herbal medication offers therapeutic benefits with good tolerability.
  • Patients taking Biocor Plus reported subjective improvements in well-being, such as reduced breathlessness and chest tightness.

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