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Prosthetic-Joint-Associated Bordetella holmesii Infection

John M Humphrey1, Sherard N J Lacaille2, Krutika Patel3

  • 1Division of Infectious Diseases, Department of Medicine , Weill Cornell Medical College.

Open Forum Infectious Diseases
|December 22, 2015
PubMed

Insights

Bordetella holmesii, a pathogen causing respiratory and invasive illness, was identified in an immunocompetent man's femoral prosthesis. This case highlights the underrecognized potential of B. holmesii in orthopedic infections.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Orthopedic Surgery

Background:

  • Bordetella holmesii is a pathogen causing pertussis-like and invasive diseases globally.
  • The role of B. holmesii in orthopedic infections is not well-established.

Purpose of the Study:

  • To report a case of Bordetella holmesii orthopedic infection.
  • To review and highlight the underrecognized role of B. holmesii in orthopedic infections.

Main Methods:

  • Case report of an immunocompetent male with B. holmesii femoral prosthesis infection.
  • Literature review of previously reported B. holmesii orthopedic infections.

Main Results:

  • A fifth case of B. holmesii orthopedic infection is described.
  • The case involved an immunocompetent individual with a femoral prosthesis infection.

Conclusions:

  • Bordetella holmesii may be an underrecognized cause of orthopedic infections.
  • Further recognition and investigation of B. holmesii in orthopedic settings are warranted.
Keywords:
Bordetella holmesiiprosthetic joint infectionseptic arthritis

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