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[Application of CAVI Index in Clinical Practice: Calculated Vascular Age as a Tool for Decision on Additional
Insights
Volumetric sphygmography can determine vascular age in cardiovascular disease patients, identifying early vascular wall changes. This accessible screening method highlights the need for further medical examination in over a quarter of patients.
Area of Science:
- Cardiovascular Medicine
- Vascular Biology
- Diagnostic Imaging
Background:
- Cardiovascular diseases (CVD) pose a significant global health burden.
- Early detection of vascular aging is crucial for CVD risk stratification.
- Volumetric sphygmography offers a non-invasive method to assess vascular health.
Purpose of the Study:
- To analyze the correlation between vascular age determined by volumetric sphygmography and chronological age in CVD patients.
- To evaluate the impact of lipid factors and carotid artery (CA) atherosclerosis on cardio-ankle vascular index (CAVI) parameters.
Main Methods:
- 185 CVD patients underwent clinical, laboratory, and instrumental examinations, including volumetric sphygmography.
- Vascular age was calculated based on the ratio of CAVI and chronological age.
- Statistical analysis explored correlations between vascular age, CAVI, lipid profiles, BMI, and CA atherosclerosis.
Main Results:
- Calculated vascular age exceeded chronological age in 23.4% of patients.
- Significant correlations were found between R-CAVI and male gender, vascular age and triglycerides (TG), L-CAVI and BMI, and R-ABI and CA atherosclerotic plaques.
- No significant differences were observed in the influence of lipid factors versus CA atherosclerosis on CAVI parameters.
Conclusions:
- Volumetric sphygmography is a reproducible and accessible method for screening early vascular wall changes.
- Determining vascular age via volumetric sphygmography indicates a need for thorough medical examination in at least 25% of CVD patients.
- This method aids in identifying individuals requiring closer monitoring for cardiovascular risk.
Objective:
to analyze correspondence between determination of vascular age of patients with cardiovascular diseases by volumetric sphygmography and their chronological age, and to assess the influence of lipid factors and atherosclerotic lesions in carotid arteries (CA) on parameters associated with the cardio-ankle vascular index (CAVI).
Material And Methods:
Clinical, laboratory and instrumental examination which included volumetric sphygmography was carried out in 185 patients with various cardiovascular diseases. Calculated vascular age was determined on the basis of graphic conversion of ratio of CAVI and true age of a patient.
Results:
Calculated vascular age exceeded chronological age in 43 patients (23.4%). Analysis of the data obtained in this subgroup, except natural interrelation between such characteristics as age, ankle-brachial index, CAVI and calculated vascular age revealed statistically significant correlations (p < 0.05) between following parameters: R-CAVI and male gender (r = 0.35), calculated vascular age (based on R-CAVI) and TG (r = -0,34), L-CAVI and BMI (r = -0.36), R-ABI and the presence of atherosclerotic plaques in carotid arteries (r = -9.34). Comparison of influence of lipid factors and CA atherosclerotic lesions on CAVI associated parameters revealed no significant differences between groups.
Conclusion:
Volumetric sphygmography with calculation of vascular age is an easily reproducible and accessible method of screening of early changes in the vascular wall. Determination of vascular age of patients with cardiovascular diseases by volumetric sphygmography suggests advisability of thorough medical examination at least in a quarter of total number of patients.
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