[Application of CAVI Index in Clinical Practice: Calculated Vascular Age as a Tool for Decision on Additional

Kardiologiia
|December 23, 2015
PubMed

Insights

Volumetric sphygmography can determine vascular age in cardiovascular disease patients, identifying early vascular wall changes. This accessible screening method highlights the need for further medical examination in over a quarter of patients.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology
  • Diagnostic Imaging

Background:

  • Cardiovascular diseases (CVD) pose a significant global health burden.
  • Early detection of vascular aging is crucial for CVD risk stratification.
  • Volumetric sphygmography offers a non-invasive method to assess vascular health.

Purpose of the Study:

  • To analyze the correlation between vascular age determined by volumetric sphygmography and chronological age in CVD patients.
  • To evaluate the impact of lipid factors and carotid artery (CA) atherosclerosis on cardio-ankle vascular index (CAVI) parameters.

Main Methods:

  • 185 CVD patients underwent clinical, laboratory, and instrumental examinations, including volumetric sphygmography.
  • Vascular age was calculated based on the ratio of CAVI and chronological age.
  • Statistical analysis explored correlations between vascular age, CAVI, lipid profiles, BMI, and CA atherosclerosis.

Main Results:

  • Calculated vascular age exceeded chronological age in 23.4% of patients.
  • Significant correlations were found between R-CAVI and male gender, vascular age and triglycerides (TG), L-CAVI and BMI, and R-ABI and CA atherosclerotic plaques.
  • No significant differences were observed in the influence of lipid factors versus CA atherosclerosis on CAVI parameters.

Conclusions:

  • Volumetric sphygmography is a reproducible and accessible method for screening early vascular wall changes.
  • Determining vascular age via volumetric sphygmography indicates a need for thorough medical examination in at least 25% of CVD patients.
  • This method aids in identifying individuals requiring closer monitoring for cardiovascular risk.
Abstract

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