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Fatal hepatic coma complicating oxymetholone therapy in multiple myeloma
Summary
Anabolic steroid oxymetholone treatment in multiple myeloma patients can lead to fatal cholestatic hepatitis. Close liver function monitoring is crucial to prevent this rare but severe complication.
Area of Science:
- Hepatology
- Oncology
- Pharmacology
Background:
- Multiple myeloma is a cancer of plasma cells.
- Anabolic steroids are sometimes used in cancer therapy.
- Cholestatic hepatitis is a liver condition causing bile flow obstruction.