Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Treatment resistant depression.

R A Remick

    Psychiatric Journal of the University of Ottawa : Revue De Psychiatrie De L'Universite D'Ottawa
    |June 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Many patients diagnosed with treatment-resistant depression (TRD) may actually have "relative" TRD. Appropriate interventions, including standard treatments, can lead to significant symptom remission in these cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Antidepressants: which one?

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Neuroleptic malignant syndrome.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Unnecessary delay in tricyclic antidepressant treatment of a patient with atrial fibrillation.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Monoamine oxidase inhibitors: clinical review.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Seasonal affective disorder.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder.

    Molecular psychiatry·2003
    Same journal

    Violence, survivors, violence.

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    Same journal

    Mental health and abortion: review and analysis.

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    Same journal

    Fluoxetine in the treatment of cyclic mood disorders.

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    Same journal

    Minor cognitive deficits and the detection of mild dementia.

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    Same journal

    Canadian Study of Health and Aging (CaSHA).

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    Same journal

    Application of Piagetian measures of cognition in severe Alzheimer's disease.

    Psychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa·1990
    See all related articles

    Area of Science:

    • Psychiatry
    • Mood Disorders Research
    • Clinical Psychology

    Background:

    • Limited scientific evaluation exists for treatment-resistant depression (TRD).
    • Conflicting definitions and concepts complicate TRD diagnosis and research.
    • The distinction between absolute and relative TRD is often unclear.

    Purpose of the Study:

    • To investigate the prevalence of relative TRD among patients diagnosed with TRD.
    • To evaluate the effectiveness of standard interventions in achieving remission for patients with TRD.

    Main Methods:

    • A study of 114 patients referred for TRD diagnosis.
    • Analysis of treatment outcomes for 98 patients receiving interventions.
    • Categorization of treatment responses based on standard therapies.

    Related Experiment Videos

    Main Results:

    • 60.2% of patients (59 out of 98) achieved complete depressive symptom remission.
    • Remission was achieved using standard treatments like tricyclic antidepressants, monoamine oxidase inhibitors, and electroconvulsive therapy.
    • The majority of successful treatments addressed what is considered 'relative' TRD.

    Conclusions:

    • A significant portion of patients diagnosed with TRD may respond to appropriate, standard interventions.
    • The concept of 'relative' TRD is crucial for accurate diagnosis and effective treatment planning.
    • Re-evaluation of TRD diagnoses and treatment strategies is warranted.