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Naturally active oligostilbenes.

Xian-Fen Wang1, Chun-Suo Yao1

  • 1a State Key Laboratory of Bioactive Substance and Function of Natural Medicines , Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100050 , China.

Journal of Asian Natural Products Research
|December 23, 2015
PubMed
Summary
This summary is machine-generated.

This review summarizes the diverse biological activities of naturally occurring oligostilbenes. It highlights recent research on these compounds, focusing on their varied effects and structures.

Keywords:
Oligostilbeneactivitystilbene dimer

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Area of Science:

  • Natural Products Chemistry
  • Pharmacology
  • Medicinal Chemistry

Background:

  • Oligostilbenes, naturally occurring compounds, are recognized for complex structures and significant biological activities.
  • Research interest in oligostilbene bioactivities has surged globally.
  • Existing literature lacks a comprehensive, systematic review of active oligostilbenes.

Purpose of the Study:

  • To provide a comprehensive and systematic summary of the diverse bioactivities of oligostilbenes.
  • To consolidate findings on oligostilbenes reported between January 2005 and December 2013.
  • To focus on the varied bioactivities associated with different oligostilbene backbones.

Main Methods:

  • Literature review encompassing scientific publications from January 2005 to December 2013.
  • Systematic collation of reported oligostilbenes and their associated bioactivities.
  • Categorization of bioactivities based on the structural diversity of oligostilbenes.

Main Results:

  • Identification of a substantial number of active oligostilbenes and novel bioactivities within the review period.
  • Documentation of a wide spectrum of biological effects attributed to oligostilbenes.
  • Highlighting the structure-activity relationships influenced by varying oligostilbene backbones.

Conclusions:

  • Oligostilbenes represent a rich source of compounds with diverse and significant biological activities.
  • This review serves as a foundational resource for understanding the therapeutic potential of oligostilbenes.
  • Further research into oligostilbenes is warranted to explore their medicinal applications.