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Optic nerve morphology in normal children.

Devang L Bhoiwala1, John W Simon2, Preethi Raghu1

  • 1Department of Ophthalmology, Albany Medical College, Albany, New York; Albany Medical College, Albany, New York.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|December 23, 2015
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This summary is machine-generated.

Pediatric optic nerves are less cupped than adults. Children

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Area of Science:

  • Ophthalmology
  • Optometry
  • Pediatric Eye Care

Background:

  • Establishing normative optical coherence tomography (OCT) data for pediatric eyes is crucial for accurate diagnosis.
  • Existing OCT normative databases primarily consist of adult data, limiting direct comparison for pediatric populations.

Purpose of the Study:

  • To expand the normative database for pediatric eyes using Optovue OCT.
  • To compare key optic nerve and retinal parameters in healthy 5-year-old children with adult normative data.

Main Methods:

  • A cross-sectional analysis of 77 healthy 5-year-old children was conducted.
  • Optic nerves were assessed using Optovue OCT, measuring retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and optic nerve head parameters.
  • Data were compared to existing Optovue adult normative databases (ages 18-60).

Main Results:

  • Children's optic nerve heads showed statistically less cupping (cup area, vertical cup-to-disk ratio, horizontal cup-to-disk ratio) compared to all adult groups (P < 0.0003).
  • No significant difference in RNFL or GCC thickness was found between children and adults aged 18-45.
  • Children exhibited thicker RNFL and GCC compared to adults aged 55-60 (P < 0.003).

Conclusions:

  • Young children possess statistically less cupped optic nerves than normal adults.
  • Pediatric RNFL and GCC thickness are greater than in older adults (55-60 years).
  • These findings contribute valuable normative OCT data for pediatric eye assessments.