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Updated: Mar 28, 2026
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
Impact of treatment strategies for open angle glaucoma on intraocular pressure: the RiGOR study
Anne L Coleman1,2, Flora C Lum2, Priscilla Velentgas3
1Jules Stein Eye Institute, David Geffen School of Medicine & Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.
Aims:
The RiGOR study's primary outcome measure was a 15% reduction in intraocular pressure (IOP) for patients with open-angle glaucoma at 1 year.
Methods:
Patients received treatment according to the ophthalmologist's usual practice.
Results:
A higher proportion of patients in the incisional and other surgery group achieved a 15% reduction in IOP than in the laser surgery or additional medication groups (82, 57, and 57% respectively). In multivariate regression analyses, incisional surgery patients were 2.7-times as likely as patients treated with additional medication to achieve a 15% reduction in IOP (odds ratio: 2.67; 95% CI: 2.01-3.57).
Conclusion:
Incisional and other surgical procedures are effective treatments. There were no differences in treatment response by race or ethnicity.
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