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Updated: Mar 28, 2026

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing
Published on: October 10, 2025
SEOM clinical guidelines for the treatment of non-small cell lung cancer (NSCLC) 2015
R García-Campelo1, R Bernabé2, M Cobo3
1Medical Oncology Department, Complejo Hospitalario Universitario A Coruña, Coruña, Spain. maria.rosario.garcia.campelo@sergas.es.
Abstract:
Lung cancer is the most common cancer worldwide as well as the leading cause of cancer related deaths as reported by Torre et al (CA Cancer J Clin 65:87-108, 2015]. Non-small cell lung cancer (NSCLC) accounts for up to 85 % of all lung cancers. Multiple advances in the staging, diagnostic procedures, therapeutic options, as well as molecular knowledge have been achieved during the past years, although the overall outlook has not greatly changed for the majority of patients with the overall 5-year survival having marginally increased over the last decade from 15.7 to 17.4 % as reported by Howlader et al. (SEER Cancer Statistics Review 2015).
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