Related Experiment Video

Updated: Mar 28, 2026

Rapid Freezing using Sandwich Freezing Device for Good Ultrastructural Preservation of Biological Specimens in Electron Microscopy
09:03

Rapid Freezing using Sandwich Freezing Device for Good Ultrastructural Preservation of Biological Specimens in Electron Microscopy

Published on: July 19, 2021

6.1K

Old and new pathogenic Nakaseomyces species: epidemiology, biology, identification, pathogenicity and antifungal

A Angoulvant1, J Guitard2, C Hennequin2

  • 1Laboratoire de Parasitologie-Mycologie, University Hospital Bicêtre, APHP, 94275 Le Kremlin-Bicêtre, France CNRS UMR 8621, Génétique Quantitative et Évolution, Univ Paris-Sud, Le Moulon, 91190 Gif-sur-Yvette, France adela.angoulvant@gmail.com.

FEMS Yeast Research
|December 23, 2015
PubMed

Insights

Candida glabrata, Candida nivariensis, and Candida bracarensis are emerging fungal pathogens. This review details their epidemiology, biology, identification, pathogenicity, and antifungal resistance.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Microbiology

Background:

  • Rising incidence of Candida infections due to immunocompromised patients, aging populations, and medical devices.
  • Candida albicans is the most common cause, but Candida glabrata is now the second most frequent agent.
  • Emergence of new Candida species, C. nivariensis and C. bracarensis, within the Nakaseomyces clade.

Purpose of the Study:

  • To review the current knowledge on three emerging Candida species: C. glabrata, C. nivariensis, and C. bracarensis.
  • To cover their epidemiology, biology, identification, pathogenicity, and antifungal resistance.
  • To provide a comprehensive resource for understanding these significant pathogens.

Main Methods:

  • Literature review synthesizing current research on the specified Candida species.
  • Analysis of epidemiological data, biological characteristics, and clinical relevance.
  • Compilation of information on identification techniques, pathogenicity factors, and antifungal susceptibility.

Main Results:

  • C. glabrata is a significant cause of candidiasis in North America and Europe.
  • C. nivariensis and C. bracarensis are newly described emerging pathogens.
  • Detailed insights into the characteristics and resistance patterns of these three species are presented.

Conclusions:

  • C. glabrata, C. nivariensis, and C. bracarensis represent a growing threat in clinical settings.
  • Understanding their unique attributes is crucial for effective diagnosis and treatment.
  • Further research is needed to combat the increasing prevalence of these Candida species.
Keywords:
C. bracarensis: epidemiologyC. glabrataC. nivariensisbiologypathogenicity

More Related Videos

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance08:45

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance

Published on: December 28, 2017

14.3K
Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis08:48

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

7.5K

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
700
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
2.4K
Antifungal Agents01:15

Antifungal Agents

Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
37
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
2.1K
Methods of Classification and Identification01:28

Methods of Classification and Identification

Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...
1.8K
Applications of Molecular Taxonomy01:20

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...
653