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Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
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Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
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[Hepatoblastoma, Etiology, Case Reports].

A Puchmajerová, A Křepelová, J Indráková

    Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti
    |December 23, 2015
    PubMed
    Summary

    Hepatoblastoma is the most common pediatric liver cancer, typically affecting children under three. Its exact cause is unknown, but genetic conditions and certain early-life factors increase risk.

    Area of Science:

    • Pediatric Oncology
    • Hepatobiliary Malignancies
    • Childhood Cancers

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