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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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c-Jun regulates adipocyte differentiation via the KLF15-mediated mode

Da Som Lee1, Hyeonjin Choi1, Baek Soo Han2

  • 1Functional Genomics Research Center, KRIBB, Daejeon 305-806, Republic of Korea.

Biochemical and Biophysical Research Communications
|December 23, 2015
PubMed
Summary

Transcription factor c-Jun suppresses adipocyte differentiation by down-regulating KLF15. This discovery offers new insights into molecular mechanisms underlying obesity and type II diabetes.

Keywords:
AdipocyteDifferentiationKLF15Obesityc-JUN

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