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Super stretchable electroactive elastomer formation driven by aniline trimer self-assembly.

Jing Chen1, Baolin Guo1, Thomas W Eyster2

  • 1Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, China.

Chemistry of Materials : a Publication of the American Chemical Society
|December 23, 2015
PubMed
Summary
This summary is machine-generated.

Researchers developed highly stretchable electroactive polyurethane-urea elastomers for soft tissue regeneration. These novel materials mimic natural tissue properties, offering potential for advanced biomedical applications like muscle and nerve repair.

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Regenerative Medicine

Background:

  • Biomedical electroactive elastomers are crucial for soft tissue replacement and regeneration.
  • Existing materials often lack the required stretchability and modulus comparable to natural soft tissues.
  • There is a significant need for advanced elastomers that can mimic the mechanical properties of muscle and nerve tissues.

Purpose of the Study:

  • To design and synthesize superiorly stretchable electroactive polyurethane-urea elastomers.
  • To investigate the mechanisms underlying the super stretchability of the developed copolymers.
  • To achieve elastomers with mechanical properties and conductivity suitable for biomedical applications.

Main Methods:

  • Synthesis of polyurethane-urea elastomers using poly(lactide), poly(ethylene glycol), and aniline trimer (AT).
  • Systematic investigation of super stretchability mechanisms using DSC, XPS, DLS, NMR, and TEM.
  • Blending of elastomers with conductive fillers (polyaniline nanofibers, carbon black) to enhance electrical conductivity.

Main Results:

  • Achieved elastomers with a strain at break >1600% and a modulus <10 MPa, similar to soft tissues.
  • Identified sphere-like hard domains self-assembled from AT segments as key to super elasticity.
  • Obtained high electrical conductivity (0.1 S/cm) upon blending with conductive fillers while maintaining excellent stretchability.

Conclusions:

  • Novel super stretchable electroactive polyurethane-urea elastomers were successfully designed and fabricated.
  • The self-assembly of AT-derived hard domains is critical for achieving exceptional stretchability.
  • These elastomers demonstrate significant potential for applications in soft tissue engineering and regeneration due to their biomimetic properties and conductivity.