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Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
Published on: May 12, 2023
A novel colorimetric and fluorescent iminocoumarin-based chemosensor for acetate ion and its application to living
Yi Jiang1, Lei-Li Sun1, Guang-Zong Ren1
1College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China.
Abstract:
A novel colorimetric and fluorescent iminocoumarin-based turn-off chemosensor for acetate ion was designed and synthesized. The chemosensor could fast detect acetate ion in a 1:1 ratio within 150 ms, which could not be affected by various coexisting anions, even F(-). Futher studies showed that the detect limit was as low as 2.05×10(-7) M, and the binding constant was determined to be 1.02×10(8) M(-1). Due to these unique properties, the chemosensor showed potential application in intracellular imaging.
