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[Association between parainfluenza virus infection and climatic factors in children]
Hua-Jie Yan1, Dong-Ping He, Jun Sheng
1Department of Pediatrics, Nanxiang Hospital of Jiading District, Shanghai 201802. dr.shaojie@ 163.com.
Insights
Human parainfluenza virus (HPIV) activity in children is linked to weather patterns. Higher temperatures and increased rainfall correlate with increased HPIV detection rates, especially in summer.
Area of Science:
- Pediatric infectious diseases
- Environmental epidemiology
- Virology
Context:
- Acute respiratory infections are common in children.
- Human parainfluenza virus (HPIV) is a significant cause of pediatric respiratory illness.
- Understanding environmental influences on HPIV is crucial for public health.
Purpose:
- To investigate the association between climatic factors and HPIV infection in children.
- To identify meteorological variables influencing HPIV prevalence.
Summary:
- A study analyzed 2,526 throat swabs from children with acute respiratory infections between 2011-2013.
- HPIV detection rates were correlated with monthly mean temperature and total rainfall.
- HPIV-1 and HPIV-2 showed seasonal variations, peaking in summer.
Impact:
- Findings highlight the role of climate in pediatric HPIV transmission.
- This research can inform public health strategies for HPIV prevention and control.
- Results emphasize the need to consider environmental factors in respiratory virus surveillance.
Objective:
To study the association between acute respiratory human parainfluenza virus (HPIV) infection and climatic factors in children.
Methods:
A total of 2 526 throat swab samples were collected from children with acute respiratory infection who visited the Pediatric Clinic of Shanghai Jiading Nanxiang Hospital between 2011 and 2013. HPIV was detected by multiplex RT-PCR. Related meteorological data were collected, including monthly mean temperature, monthly mean humidity, and monthly total rainfall. The association between HPIV detection rate and climatic factors was analyzed by Spearman's or Pearson test.
Results:
During the three years, the overall HPIV detection rate was 5.62% (142/2 526), and HPIV-1 was the most common type (46.5%), followed by HPIV-3 (31.0%), HPIV-2 (17.6%), and HPIV-4 (4.9%). There were significant differences in the detection rates of HPIV-1 and HPIV-2 in different seasons, and the detection rates of both were the highest in summer (P<0.05). HPIV positive rate was positively correlated with monthly mean temperature (r=0.598; P<0.01) and monthly total rainfall (rs=0.602; P<0.01).
Conclusions:
The activity of HPIV in children is correlated with climatic factors, particularly temperature and rainfall.
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