Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

12.2K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
12.2K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

22.0K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
22.0K
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

15.1K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
15.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A phase I/II study of the safety and efficacy of telaglenastat (CB-839) in combination with nivolumab in patients with metastatic melanoma, renal cell carcinoma, and non-small-cell lung cancer.

ESMO open·2025
Same author

Fungal Planet description sheets: 1478-1549.

Persoonia·2024
Same author

A multicenter, randomized phase 2 study to establish combinations of CBP501, cisplatin and nivolumab for ≥3rd-line treatment of patients with advanced pancreatic adenocarcinoma.

European journal of cancer (Oxford, England : 1990)·2024
Same author

Assessment of cannabidiol use in pets according to a national survey in the USA.

The Journal of small animal practice·2023
Same author

Prospects for beyond the Standard Model physics searches at the Deep Underground Neutrino Experiment: DUNE Collaboration.

The European physical journal. C, Particles and fields·2021
Same author

Measurement of single-diffractive dijet production in proton-proton collisions at <math> </math> with the CMS and TOTEM experiments.

The European physical journal. C, Particles and fields·2020

Related Experiment Video

Updated: Mar 28, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
12:22

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

9.1K

Compact étendue-preserving light-mixing optics.

S Sorgato, R Mohedano, J Chaves

    Optics Express
    |December 25, 2015
    PubMed
    Summary

    A new compact optic, the Freeform Shell-Mixer, uniformly mixes colors from multicolor light sources like LEDs. This injection-moldable device ensures homogeneous light mixing and maintains luminaire performance with high efficiency.

    More Related Videos

    Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
    08:39

    Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

    Published on: January 28, 2019

    10.5K
    A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors
    11:15

    A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors

    Published on: May 30, 2016

    26.5K

    Related Experiment Videos

    Last Updated: Mar 28, 2026

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT
    12:22

    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

    Published on: August 4, 2018

    9.1K
    Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator
    08:39

    Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

    Published on: January 28, 2019

    10.5K
    A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors
    11:15

    A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors

    Published on: May 30, 2016

    26.5K

    Area of Science:

    • Optics and Photonics
    • Illumination Engineering

    Background:

    • Achieving uniform color mixing in multicolor light sources, such as multi-chip LEDs, is crucial for many lighting applications.
    • Existing solutions can be bulky or inefficient, limiting their integration into compact luminaires.

    Purpose of the Study:

    • To introduce a novel, compact freeform optic designed for homogeneous color mixing of multicolor light sources.
    • To evaluate the optical performance, efficiency, and compatibility of the proposed optic with existing luminaire designs.

    Main Methods:

    • Design and simulation of a freeform optic, termed the "Freeform Shell-Mixer", utilizing étendue-conserving Köhler integration.
    • Ray tracing analysis to model light mixing, virtual source characteristics, and emission patterns.
    • Assessment of manufacturability through compatibility with injection molding.

    Main Results:

    • The Freeform Shell-Mixer achieves over 95% optical efficiency.
    • It transforms a multicolor source into a virtual source with uniform color mixing.
    • The optic's minimal size (2x source size) and preserved emission pattern ensure luminaire performance.

    Conclusions:

    • The Freeform Shell-Mixer offers an efficient and compact solution for homogeneous color mixing in LED lighting.
    • Its design is compatible with mass production via injection molding.
    • The optic effectively preserves luminaire performance while enhancing color uniformity.