Related Experiment Video
Updated: Mar 28, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Use of diverging apertures to minimize the edge scatter in passive scattering proton therapy
Tianyu Zhao1, Bin Cai, Baozhou Sun
1Washington University School of Medicine. tzhao@radonc.wustl.edu.
Abstract:
The purpose of this study was to evaluate the use of diverging-cut aperture to minimize collimator contamination in proton therapy. Two sets of apertures with nondivergent and divergent edge were fabricated to produce a 10 cm × 10 cm field at the radiation isocenter of a single-room proton therapy unit. Transverse profiles were acquired in a scanning water tank with both aperture sets. Up to 9.5% extra dose was observed from aperture scattering near the field edges with the nondivergent aperture set at 2 cm above the water surface and remained 3.0% at depth of 10 cm. For the divergent set, the contamination was reduced to less than 3.5% and 1.3%, respectively. Our study demonstrated that scattering from apertures contaminated the dose distribution near the field edge at shallow depth. A diverging-cut aperture was capable of reducing the contamination and is recommended for use in passive scattering proton therapy, especially when critical organs are lateral and proximal to the target at shallow depth.
More Related Videos
Related Concept Videos
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
Absorption of Radiation
Radiation: Applications
The average...

