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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
[The nineteenth-century epidemic waves of influenza]
Chiara Beatrice Vicentini1, Enrica Guidi2, Silvia Lupi2
1Dipartimento di Scienze della Vita e Biotecnologie, Università di Ferrara, Ferrara, Italy.
Abstract:
The retrospective analysis undertaken by our working group in the sphere of infectious diseases, with particular emphasis on nineteenth-century epidemics, regards influenza, which according to the scholar W.I. Beveridge, was defined as "one of the greatest enemies of man". The work is divided into three parts: influenza, its historical names and the characteristics of the recurrent epidemics from the sixteenth to the nineteenth century among the world's population. This part is followed by treatment and remedial action in the nineteenth century. The third, deals with death attributed to influenza and its complications observed in the city of Ferrara in the years when outbreaks occurred, affecting the majority of the populations: 1830-1833, 1836-1837, 1847-1848, 1857-1858, 1873-1875, 1889-1892, the latter known as the great pandemic.
Insights
This study analyzes historical influenza epidemics from the 16th to 19th centuries, focusing on treatments and mortality in Ferrara. It highlights influenza
Area of Science:
- Historical epidemiology
- Infectious disease analysis
Background:
- Focuses on influenza, a significant historical infectious disease.
- Examines epidemics from the 16th to the 19th century.
Observation:
- Details historical names and characteristics of influenza epidemics.
- Investigates 19th-century treatments and remedial actions.
- Analyzes influenza-attributed deaths and complications in Ferrara during specific epidemic years (1830-1892).
Findings:
- Recurrent influenza epidemics significantly impacted global populations.
- 19th-century interventions varied, with influenza remaining a major health threat.
- Specific outbreaks in Ferrara show substantial mortality and complications.
Implications:
- Provides insights into the long-term impact of influenza pandemics.
- Informs historical understanding of public health responses to epidemics.
- Contributes to the study of infectious disease evolution and control.
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