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[AIDS and the fetus].

R Henrion

    Bulletin De L'Academie Nationale De Medecine
    |March 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Preventing mother-to-child transmission of acquired immunodeficiency syndrome (AIDS) is crucial in Europe. Strategies focus on preventing HIV transmission during pregnancy, birth, and breastfeeding, as effective treatments are limited.

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    Area of Science:

    • Infectious Diseases
    • Public Health
    • Pediatrics

    Context:

    • Acquired immunodeficiency syndrome (AIDS) presents a significant challenge for women and children in Europe.
    • Intravenous drug abuse is a primary transmission route, with heterosexual transmission increasingly prevalent.
    • Human immunodeficiency virus (HIV) seropositive mothers pose a substantial risk of perinatal transmission to their infants.

    Purpose:

    • To review current understanding and management of acquired immunodeficiency syndrome (AIDS) in European women and children.
    • To highlight transmission routes, including intravenous drug abuse, heterosexual contact, and perinatal transmission.
    • To discuss obstetric practices and preventive measures for human immunodeficiency virus (HIV) in pregnancy.

    Summary:

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  • Perinatal human immunodeficiency virus (HIV) transmission rates from seropositive mothers range from 30% to 40%, with significant morbidity and mortality in affected infants.
  • Evidence supports transplacental transmission, with intrapartum transmission also a possibility.
  • Recommended preventive strategies include avoiding breastfeeding and considering pregnancy termination, alongside ongoing research into prenatal diagnosis and antiviral therapies.

    • Impact:

    • Highlights the critical need for preventive measures against acquired immunodeficiency syndrome (AIDS) in vulnerable populations.
    • Underscores the importance of further research into perinatal human immunodeficiency virus (HIV) transmission routes and interventions.
    • Informs obstetric and public health strategies to mitigate the impact of HIV on women and children in Europe.