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In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
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UHRF1 is a sensor for DNA interstrand crosslinks

Chih-Chao Liang1, Martin A Cohn1

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Oncotarget
|December 25, 2015
PubMed
Summary

No abstract available in PubMed .

Keywords:
FANCD2Fanconi anemiaICL repairUHRF1ubiquitin

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