Related Experiment Video
Updated: Mar 28, 2026

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
Published on: January 24, 2020
Differentiating Aging Among Adults With Down Syndrome and Comorbid Dementia or Psychopathology
Anna J Esbensen1, Emily Boshkoff Johnson1, Joseph L Amaral1
1Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
Abstract:
Differences were examined between three groups of adults with Down syndrome in their behavioral presentation, social life/activities, health, and support needs. We compared those with comorbid dementia, with comorbid psychopathology, and with no comorbid conditions. Adults with comorbid dementia were more likely to be older, have lower functional abilities, have worse health and more health conditions, and need more support in self-care. Adults with comorbid psychopathology were more likely to exhibit more behavior problems and to be living at home with their families. Adults with no comorbidities were most likely to be involved in community employment. Differences in behavioral presentation can help facilitate clinical diagnoses in aging in Down syndrome, and implications for differential diagnosis and service supports are discussed.
More Related Videos
08:29Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
Published on: December 18, 2016
10:13Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Related Concept Videos
Cognitive Development During Adulthood
Pharmacodynamics in Geriatric Patients: Effects of Age
Dementia
The progression of dementia is generally gradual....
Drug Dosing: Geriatric Patients
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...