Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cough, codeine and confusion.

David O Reilly1, Mathew Thomas2, Edina Moylett3

  • 1School of Medicine, National University of Ireland, Galway, HSE West, Galway, Connacht, Ireland Donegal Clinical Research Academy, Letterkenny General Hospital, HSE West, Letterkenny, Ulster, Ireland.

BMJ Case Reports
|December 25, 2015
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Paraconduit hernia after esophagectomy: Impact of operative technique on its incidence and recurrence.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Clinical Outcomes of Pre-Transplant Cardiac Prehabilitation in the ICU on Impella 5.5.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026
Same author

Comparison of lung function and survival in high-risk <i>vs.</i> standard risk lung volume reduction surgery patients.

Journal of thoracic disease·2026
Same author

The Use of the Split Jejunal and Colon Patch Within the Oral Cavity: A Systematic Review and Meta-Analysis.

The Journal of craniofacial surgery·2026
Same author

Early Trends After Safety Net Policy Introduction for Kidney After Lung Transplantation.

Chest·2026
Same author

Time to first passage of meconium in 800 Irish-born healthy term infants: a real-time observational study.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same journal

Early onset cerebral oedema in adult diabetic ketoacidosis with complete resolution.

BMJ case reports·2026
Same journal

Third salvage haematopoietic stem cell transplantation in a child with very early-onset IBD due to interleukin-10 receptor deficiency.

BMJ case reports·2026
Same journal

Fungal keratitis caused by <i>Trichomonascus ciferrii</i> in an immunocompetent adult.

BMJ case reports·2026
Same journal

An unusual cause of acute small bowel obstruction in a child: multiple trichobezoars diagnosed on CT.

BMJ case reports·2026
Same journal

Massive haemoptysis secondary to pulmonary artery aneurysms in Hughes-Stovin syndrome: a variant of Behçet's disease managed with immunosuppression and endovascular embolisation.

BMJ case reports·2026
Same journal

The blue dilemma: a rare presentation of dual hemoglobinopathy in a pregnant patient.

BMJ case reports·2026
See all related articles

Over-the-counter codeine cough preparations pose risks, including acute confusional states and respiratory depression, especially in children. Their efficacy is unproven, making their use potentially unwarranted.

Area of Science:

  • Pharmacology
  • Pediatric Medicine
  • Toxicology

Background:

  • Codeine is frequently prescribed for cough and cold symptoms, with over-the-counter (OTC) availability.
  • Concerns regarding codeine's safety and efficacy in pediatric populations have increased.

Observation:

  • A case of acute confusional state in a 14-year-old girl was linked to inappropriate codeine use.
  • Previous reports highlight codeine-related deaths in children, primarily due to respiratory depression.

Findings:

  • OTC codeine cough suppressants lack proven efficacy.
  • Codeine use is associated with risks of acute intoxication and dependence in both adults and adolescents.

Implications:

  • The risks of codeine, including intoxication and dependence, may outweigh benefits, especially given absent efficacy data.

Related Experiment Videos

  • The use of OTC codeine preparations warrants re-evaluation due to potential harm in pediatric and adolescent populations.
  • Clinical guidelines and public health messaging should address the risks of codeine, particularly OTC formulations.