Related Experiment Video
Updated: Mar 28, 2026

09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
2.9K
Fluoroscopically-guided epidural blood patch for spontaneous intracranial hypotension
Manish Shah1, David M Giampetro2, Paul Kalapos3
1Department of Anesthesiology, Penn State Hershey Medical Center, Pennsylvania, USA.
Journal of Anaesthesiology, Clinical Pharmacology
|December 25, 2015
Summary
Image-guided epidural blood patches effectively treat spontaneous intracranial hypotension when conservative methods fail. This minimally invasive procedure offers significant long-term symptom relief and resolves cerebrospinal fluid (CSF) leaks.
Area of Science:
- Neurology
- Neurosurgery
- Radiology
Background:
- Spontaneous intracranial hypotension (SIH) is a debilitating condition caused by cerebrospinal fluid (CSF) leaks.
- Conservative treatments often fail to resolve SIH, necessitating alternative therapeutic strategies.
Observation:
- Three patients with persistent SIH, unresponsive to conservative management, were treated with image-guided epidural blood patching.
- The procedure targeted the suspected site of CSF leakage.
Findings:
- All three patients experienced significant and sustained improvement in clinical symptoms.
- Radiological evidence of CSF leaks also showed marked resolution post-treatment.
- Epidural blood patching proved effective in managing SIH.
Implications:
- Image-guided epidural blood patching is a viable and effective treatment for spontaneous intracranial hypotension.
- This minimally invasive approach offers a promising alternative for patients refractory to conservative care.
- Further research may elucidate optimal techniques and patient selection for this intervention.
Keywords:
Cerebrospinal spinal fluid leakconnective tissueepidural blood patchfluoroscopyheadacheintracranial hypotensionmagnetic resonance imagingmyelographyMore Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
960
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
960
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
1.9K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
1.9K
Epistaxis
714
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
714

