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Abrupt Development of Plasma Cell Leukemia in a Patient with Chronic Anemia under Follow-up
Mohamad Reza Farzaneh1, Ali Moradi2, Mohammad Reza Ravanbod3
1Pathology Department, Bushehr University of Medical Sciences, Bushehr, Iran. mrfarzaneh@yahoo.com.
Abstract:
Plasma cell leukemia (PCL) is a very rare and progressive hematologic malignancy with unpleasant prognosis, which present with monoclonal proliferation of plasma cells in peripheral blood. Here we report a 52-year-old female case of PCL which diagnosed by morphology and immunohistochemistery (IHC) study. IHC revealed CD20+/CD38+/CD138+/CD56-/kappa-/lambda+. We diagnose PCL on peripheral blood. IHC can be helpful for prognostic determination.
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