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Picomolar detection of carcinoembryonic antigen in whole blood using microfluidics and surface-enhanced Raman
Kun Zou1, Zhigang Gao2,3, Quanfeng Deng2,3
1The Second Hospital of Dalian Medical University, Dalian, P. R. China.
Electrophoresis
|December 26, 2015
Abstract:
Carcinoembryonic antigen (CEA) is a wide-spectrum biomarker. Clinically, we generally use serum sample to detect CEA, which needs to be centrifuged to pretreat the raw blood sample. In this study, we realized direct CEA detection in raw blood samples exploiting microfluidics. The LOD was as low as 10(-12) M.
