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Updated: Mar 28, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
Ulnar nerve sonography in leprosy neuropathy.
Zhu Wang1, Da-Yue Liu2, Yang-Yang Lei1
1Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University, NO. 58 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.
Leprosy can affect the ulnar nerve, causing sensory and motor issues. Characteristic ultrasound findings, including nerve thickening and increased blood flow, can aid in diagnosing this rare condition.
Area of Science:
- Neurology
- Radiology
- Infectious Diseases
Background:
- Leprosy, a chronic infectious disease, primarily affects peripheral nerves.
- Early diagnosis is crucial for preventing nerve damage and disability.
- Ultrasound is an emerging tool for peripheral nerve evaluation.
Observation:
- A 23-year-old woman presented with right forearm sensory and motor dysfunction.
- Ultrasound revealed ulnar nerve trunk thickening, hypoechogenicity, and increased vascularity.
- Histopathology confirmed granulomatous inflammation consistent with leprosy.
Findings:
- Sonographic features of ulnar nerve leprosy include nerve thickening and altered echogenicity.
- Color Doppler demonstrated significantly increased blood supply in the affected nerve.
- Histopathological analysis revealed granulomatous nodules with specific cellular infiltrates and vascular proliferation.
Implications:
- This case highlights characteristic ultrasound findings for diagnosing ulnar nerve leprosy.
- Increased awareness of these sonographic features can aid clinicians in identifying leprosy.
- Recognizing leprosy's neurological manifestations is vital, especially given its declining but persistent incidence.
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