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Injectable intraocular telescope: Pilot study.

Muhammad A Qureshi¹, Scott J Robbie¹, Juan Tabernero¹

¹From the London Eye Hospital (Qureshi), London Eye Hospital Pharma (Qureshi, Robbie), London, United Kingdom; Laboratorio de Optica (Tabernero, Artal), Universidad de Murcia, Murcia, Spain.

Journal of Cataract and Refractive Surgery

|December 26, 2015

Summary

This pilot study found that an injectable intraocular miniature telescope (iolAMD) is safe and improves visual acuity in patients with age-related macular degeneration. Further research is needed to confirm long-term efficacy for daily activities.

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Area of Science:

Ophthalmology
Biomedical Engineering

Background:

Age-related macular degeneration (AMD) is a leading cause of vision loss.
Current treatments for advanced AMD have limitations.

Purpose of the Study:

To assess the feasibility and safety of a novel injectable intraocular miniature telescope (iolAMD) for patients with dry age-related macular degeneration.

Main Methods:

A prospective interventional pilot study was conducted at London Eye Hospital.
Two intraocular lenses (IOLs) in a Galilean telescope configuration were implanted in eyes with dry AMD.
Safety and visual function were monitored for 4 months.

Main Results:

No significant intraoperative or postoperative complications occurred.
Mean corrected distance visual acuity (CDVA) improved by 67% (from 0.12 to 0.20).
Endothelial cell density decreased by 18%, and induced astigmatism was 0.5 D.

Conclusions:

The injectable intraocular miniature telescope (iolAMD) appears safe in the short-to-medium term.
The device demonstrated potential for improving visual function in AMD patients.
Further studies are required to evaluate long-term safety and efficacy for daily activities.