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Acute Recurrent Pancreatitis in Children: A Study From the Pediatric Health Information System
Chaitanya Pant1, Thomas J Sferra, Brian R Lee
1*Kansas University Medical Center, Kansas City †UH Rainbow Babies & Children's Hospital, Cleveland, OH ‡Children's Mercy Hospital, Kansas City, MO.
Insights
Pediatric acute recurrent pancreatitis (ARP) affects 42% of children hospitalized for acute pancreatitis (AP). Younger children and those with severe initial AP episodes face higher ARP risks, often requiring intensive care.
Area of Science:
- Pediatric Gastroenterology
- Clinical Epidemiology
Background:
- Acute pancreatitis (AP) is a significant concern in pediatric healthcare.
- Understanding the patterns and risk factors of recurrent AP is crucial for improving patient outcomes.
Purpose of the Study:
- To investigate the incidence, characteristics, and risk factors of acute recurrent pancreatitis (ARP) in children.
- To identify patient and disease factors associated with ARP and its associated healthcare utilization.
Main Methods:
- Retrospective analysis of a national health care database from 2002 to 2014.
- Inclusion of all pediatric patients diagnosed with AP, focusing on index hospitalizations and subsequent rehospitalizations.
- Statistical analysis to determine the prevalence of ARP and identify associated risk factors.
Main Results:
- Out of 26,435 children with AP, 4,489 (42%) experienced 15,787 rehospitalizations.
- Children had a median of 2 ARP-related hospitalizations with a median 86-day interval between admissions.
- Younger age and a more severe index AP episode were significant risk factors for ARP.
- ARP-related hospitalizations showed increased intensive care unit (ICU) care requirements compared to index AP episodes.
Conclusions:
- Acute recurrent pancreatitis is a common complication in pediatric AP, affecting a substantial proportion of patients.
- Risk stratification for ARP should consider patient age and initial disease severity.
- ARP necessitates more intensive medical care, highlighting the need for effective management strategies.
Abstract:
We investigated acute recurrent pancreatitis (ARP) in children using a national health care database. From 2002 to 2014, 26,435 children had a diagnosis of acute pancreatitis (AP); 10,648 discharges were index hospitalizations. A total of 6159 children had a single hospitalization for AP, whereas 4489 (42%) children underwent 15,787 rehospitalizations. Children experienced a median of 2 ARP-related hospitalizations with a median time between admissions of 86 days. Younger patients with a more severe index episode of AP were at a higher risk of ARP. ARP-related hospitalizations had an increased requirement for intensive care unit care compared with an index episode of AP.
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