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C1q/TNF-related protein-1: an adipokine marking and promoting atherosclerosis

Lin Lu1, Rui Yan Zhang2, Xiao Qun Wang1

  • 1Department of Cardiology, Rui Jin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China Institute of Cardiovascular Diseases, Shanghai Jiaotong University School of Medicine, Shanghai 200025, People's Republic of China.

European Heart Journal
|December 26, 2015
PubMed
Summary

C1q/TNF-related protein-1 (CTRP1) is elevated in coronary artery disease (CAD) patients and promotes atherosclerosis by increasing inflammation and monocyte adhesion. CTRP1 is a potential therapeutic target for preventing CAD progression.

Keywords:
AdipokinesAtherosclerosisCTRP1Coronary artery diseaseEndothelium

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