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Sarcoidosis-lymphoma syndrome
Anahy M Brandy-García1, Luis Caminal-Montero2, María Soledad Fernández-García3
1Servicio de Reumatología, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
Reumatologia Clinica
|December 27, 2015
Summary
A rare case of central nervous system involvement in sarcoidosis is presented, where a large B-cell lymphoma was diagnosed in the optic nerve. This highlights an atypical tumor association with sarcoidosis.
Area of Science:
- Neurology
- Oncology
- Ophthalmology
Background:
- Sarcoidosis is a multisystem inflammatory disease.
- Central nervous system (CNS) involvement is rare but serious.
- Ocular manifestations can occur in sarcoidosis.
Observation:
- A 65-year-old female with known sarcoidosis developed diplopia.
- Imaging revealed a mass in the right intraconal space involving the optic nerve and lymph nodes.
- Standard analyses were normal.
Findings:
- Biopsy confirmed large B-cell lymphoma.
- This represents an atypical tumor manifestation associated with sarcoidosis.
- The lymphoma was located in the right optic nerve sheath.
Implications:
- This case underscores the importance of considering neoplastic processes in sarcoidosis patients with CNS symptoms.
- Early diagnosis and appropriate treatment are crucial for managing CNS lymphoma in sarcoidosis.
- Further research into the link between sarcoidosis and B-cell lymphoma is warranted.
Keywords:
DiplopiaDiplopíaLinfomaLymphomaNeurosarcoidoisSarcoidosisSarcoidosis-lymphoma syndromeSíndrome sarcoidosis-linfomaMore Related Videos
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