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Updated: Mar 28, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Articular manifestations in patients with Lyme disease
María Esther Vázquez-López1, Carolina Díez-Morrondo2, Amalia Sánchez-Andrade3
1Servicio de Pediatría, Hospital Universitario Lucus Agusti, Lugo, España.
Objectives:
To determine the percentage of Lyme patients with articular manifestations in NW Spain and to know their evolution and response to treatment.
Patients:
A retrospective study (2006-2013) was performed using medical histories of confirmed cases of Lyme disease showing articular manifestations. Clinical and laboratory characteristics, together with the treatment and evolution of the patients, were analysed.
Results:
Seventeen out of 108 LD confirmed patients (15.7%) showed articular manifestations. Regarding those 17 patients, 64.7%, 29.4% and 5.9% presented arthritis, arthralgia and bursitis, respectively. The knee was the most affected joint. Articular manifestations were often associated to neurological, dermatological and cardiac pathologies. Otherwise, most patients were in Stage III. The 11.8% of the cases progressed to a recurrent chronic arthritis despite the administration of an appropriate treatment.
Conclusions:
Lyme disease patients showing articular manifestations should be included in the diagnosis of articular affections in areas of high risk of hard tick bite, in order to establish a suitable and early treatment and to avoid sequels.
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