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Updated: Mar 28, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Prolonged Barium-Impaction Ileus in Two Lung Transplant Recipients With Systemic Sclerosis: Case Report.
S Tokman1, S R Hays2, L E Leard2
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of California, San Francisco, California; Advanced Lung Disease and Lung Transplant Program, Norton Thoracic Institute, St Joseph's Hospital and Medical Center, Phoenix, Arizona.
Lung transplantation can save lives for systemic sclerosis patients. However, gastrointestinal issues, like barium-impaction ileus after feeding tube use, can complicate outcomes.
Area of Science:
- Medicine
- Gastroenterology
- Pulmonology
Background:
- Systemic sclerosis (SSc) patients with end-stage lung disease may undergo lung transplantation.
- Gastrointestinal (GI) manifestations of SSc can negatively impact transplant outcomes.
- Enteral feeding via gastrojejunal tubes is a strategy for managing SSc-related esophageal and gastric disease.
Observation:
- This report details two lung transplant recipients with SSc.
- Both patients developed severe, prolonged barium-impaction ileus.
- The ileus occurred after the insertion of a percutaneous gastrojejunal feeding tube.
Findings:
- Percutaneous gastrojejunal feeding tubes can precipitate severe gastrointestinal complications in SSc lung transplant recipients.
- Barium-impaction ileus is a significant risk in this patient population.
- The interaction between SSc-related GI dysmotility and feeding tube use requires careful consideration.
Implications:
- Clinicians should exercise caution when using percutaneous gastrojejunal feeding tubes in SSc lung transplant candidates and recipients.
- Alternative nutritional support strategies may be necessary to mitigate the risk of ileus.
- Further research is needed to optimize GI management and improve transplant outcomes in SSc patients.
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