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Published on: February 26, 2013
Mycophenolate mofetil therapy for two cases of antiphospholipid antibody-associated chorea
Koji Yokoyama1, Masaaki Mori2, Akira Yoshida1
1a Department of Pediatrics , Japanese Red Cross Wakayama Medical Center , Wakayama , Japan and.
Abstract:
Chorea is associated with involuntary movement and may occur via an autoimmune mechanism. Until now, we treated immune-mediated chorea with glucocorticoids and cyclophosphamide as the efficacy of mycophenolate mofetil (MMF) therapy for this condition was unknown. Here, we report two cases of antiphospholipid antibody (aPL)-associated chorea that were cured by MMF. Measurement of aPL could help for future management of chorea patients. This report provides new insight into the beneficial effects of MMF on aPL-associated chorea.
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