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Updated: Mar 28, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
Mathematical Models of College Myopia
Peter R Greene1, Zachary W Grill2, Antonio Medina3
1B.G.K.T. Consulting Ltd., Bioengineering, Huntington, New York, 11743, +1 631 935 56 66; prgreeneBGKT@gmail.com.
Abstract:
Experimental design phase of a pilot study at Annapolis is described, using reading glasses, +1.5 D. to +3.0 D. to alleviate college myopia. College students often become 1.0 to 2.0 diopters more myopic, so reading glasses were explored to partially cancel the effects of the study environment. N = 25 different sets of (+)Add lenses are evaluated, for required adjustment period and reading comfort. Three computer models are developed to predict refraction versus time. Basic control system equations predict exponential myopia shift of refractive state R(t) with time constant t0 = 100 days. Linear, exponential and Gompertz computer results are compared calculating refraction R(t) during the college years, showing correlation coefficients |r| = 0.96 to 0.97, accurate +/-0.31 D. over a 14 year interval. Typical college myopia rate is -0.3 to -0.4 D/yr. Reading glasses may be a simple, practical solution to stabilize college myopia.
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